Research topics
Ten research areas. Each maps to the claims graded within it, the compounds examined for that endpoint, and the studies underneath. Topic names use research terminology deliberately, in place of consumer-health framing.
Metabolic & Body-Composition Research
Incretin signalling, energy balance, adiposity, glycaemic parameters, and body-composition endpoints as measured in published trials.
7 compounds · 9 graded claims · 7 with human evidence
Semaglutide, Tirzepatide, Retatrutide, Cagrilintide, Tesamorelin, AOD-9604, 5-Amino-1MQ
Musculoskeletal Recovery Research
Tendon, ligament, muscle, and connective-tissue repair endpoints. Note that this area is dominated by animal models.
2 compounds · 3 graded claims · 0 with human evidence
BPC-157, TB-500 / Thymosin beta-4
Sleep & Circadian Research
Sleep architecture, slow-wave sleep, circadian signalling, and related polysomnographic endpoints.
1 compound · 1 graded claim · 1 with human evidence
DSIP
Cognitive & Neurologic Research
Neurotrophic signalling, memory and attention endpoints, neuroprotection, and neuroinflammation.
2 compounds · 2 graded claims · 2 with human evidence
Semax, Selank
Dermatologic & Tissue Research
Dermal matrix remodelling, collagen synthesis, wound healing, pigmentation, and follicular endpoints.
2 compounds · 2 graded claims · 2 with human evidence
GHK-Cu, Melanotan II
Aging & Longevity Research
Cellular senescence, telomere biology, NAD+ metabolism, and biomarkers proposed as ageing surrogates.
2 compounds · 3 graded claims · 2 with human evidence
Epitalon, NAD+ and precursors
GH-Axis Research
Growth-hormone-releasing hormone analogues, secretagogues, IGF-1 response, and pulsatility.
5 compounds · 5 graded claims · 4 with human evidence
Tesamorelin, Ipamorelin, CJC-1295, Sermorelin, Hexarelin
Immune Signalling Research
Thymic peptides, T-cell modulation, inflammatory signalling, and infection-related endpoints.
1 compound · 1 graded claim · 1 with human evidence
Thymosin alpha-1
Mitochondrial Research
Mitochondrial-derived peptides, cardiolipin interaction, oxidative phosphorylation, and exercise capacity.
2 compounds · 2 graded claims · 1 with human evidence
MOTS-c, Elamipretide (SS-31)
Sexual Health Research
Melanocortin signalling and sexual-desire or erectile-function endpoints as measured by validated instruments.
1 compound · 1 graded claim · 1 with human evidence
Bremelanotide