Peptide Protocol IQ
Anxiety and cognitive support

Russian Nootropic Stack

Selank with Semax

Also called selank semax, semax selank stack, russian nootropic stack, nasal nootropic stack

Two intranasal peptides with real Russian trials behind them, and not one usable per-dose figure in the published record.

XInsufficient / conflictingevidence for this combination, not for the compounds individually

Combination evidence: Insufficient / conflicting

This is an unusual case and worth reading carefully. Both compounds have genuine randomised human trials, published and indexed, with real identifiers. Neither trial states a per-administration amount. The Semax stroke trial reports 6,000 µg per day without saying how it was divided; the Selank anxiety trial reports no amount at all. So every figure below is community practice, on a site that has the trials catalogued and could not use them.

Where every number on this page comes from

Each quantity carries one of these five labels. They are not interchangeable, and the difference between the first and the last is the difference between a regulated finding and a rumour with a number attached.

FDA labelling
This figure appears in FDA-approved product labelling for an approved indication. It is the strongest warrant on this site.
Published study arm
This figure is the quantity administered in a named arm of the linked study. It describes what was studied, not what is advised.
Clinical guideline
This figure appears in published clinical or professional guidance.
Manufacturer protocol
This figure comes from a manufacturer or investigator document rather than from peer-reviewed literature.
Community practice — no trial
No clinical trial has tested this figure. It reflects what is commonly reported in practice and carries no evidentiary weight. It is shown because it is what circulates, and because showing it with this label is more useful than pretending it does not exist.
Plan against

The figure most often reported for each compound. Where a compound has no separately sourced figure at this level, its most commonly reported figure is used instead, and the citation beneath it says so.

Duration

4 weeks

1 phase

Administrations

112

about 28/week at peak

Vials required

7

2 compounds

Cost at this plan

$164.00

Pure Health Peptides, list price

Phase by phase

Weeks 14 · 4 weeks

Continuous run

Both intranasal, both several times a day. Four weeks reflects the course lengths described in the Russian literature, which ran five to ten days at a time with breaks between courses rather than continuously.

Semax

2 times daily · Intranasal

Lowest sourced, per dose

100 mcgCommunity practice — no trial

Commonly reported lower figure per administration, derived from drop volume at 0.1% concentration. The published trials report per-day amounts only.

Most commonly reported, per dose

300 mcgCommunity practice — no trial

Modal reported figure per administration in practice. The published trials report per-day amounts only.

Highest sourced, per dose

600 mcgCommunity practice — no trial

Commonly reported upper figure per administration at 1% concentration. The published trials report per-day amounts only.

Prepared at 5 mg in 2 mL

Every quantity above is one administration. At 2 times daily, that is 4.20 mg per week.

Concentration2.50 mg/mLDraw volume0.120 mL
Pull to (U-100)12.0 unitsDoses per vial16
This phase56 administrationsVials, this phase4

Why it is here

ACTH(4-10) analogue studied in Russian stroke and cognitive literature.

What is not known

The 0.1% and 1% solutions differ tenfold in mass per drop, and product listings often omit which is which. A figure quoted without its concentration is not a figure. The stroke trial's 6,000 µg per day cannot be converted into a per-administration amount because the division is not published.

Selank

2 times daily · Intranasal

Lowest sourced, per dose

250 mcgCommunity practice — no trial

Commonly reported lower figure per administration in practice. The published trials report no amount at all.

Most commonly reported, per dose

500 mcgCommunity practice — no trial

Modal reported figure per administration in practice. The published trials report no amount at all.

Highest sourced, per dose

750 mcgCommunity practice — no trial

Commonly reported upper figure per administration in practice. The published trials report no amount at all.

Prepared at 10 mg in 2 mL

Every quantity above is one administration. At 2 times daily, that is 7.00 mg per week.

Concentration5.00 mg/mLDraw volume0.100 mL
Pull to (U-100)10.0 unitsDoses per vial20
This phase56 administrationsVials, this phase3

Why it is here

Tuftsin analogue studied against a benzodiazepine comparator in generalised anxiety and neurasthenia.

What is not known

The 2008 trial, PMID 18454096, is real, randomised, and reports an anxiolytic effect comparable to medazepam. Its abstract states no amount, no concentration, no route detail and no frequency. There is no study arm here to attribute a number to.

What you would need to buy

Vial counts are computed by simulating consumption, not by dividing total milligrams. Those two disagree whenever a vial cannot be finished, which is most of the time, and dividing under-buys.

CompoundVialAdministrationsTotal materialVials
SemaxContinuous run5 mg5616.80 mg4
SelankContinuous run10 mg5628.00 mg3
Total1127

What it would cost

List prices from each vendor’s own product pages, with the date each figure was read. Quantity tiers are applied where a vendor publishes them.

Loti Labs

Prices as of 2026-08-24

$330.61

$11.81/day · $359.42/month

SemaxSemax 5mg · 5 mg$7.76/mg listed · $9.24/mg after what expires unused4 × $38.79$155.16
SelankSelank 10mg · 10 mg$4.85/mg listed · $5.20/mg after what expires unused3 × $48.49$145.47
Bacteriostatic water10ML Reconstitution Solution · 10 mLThis plan uses 14.0 mL across every reconstitution. 6.0 mL is left over, because bottles do not divide.2 × $14.99$29.98
Syringes112 administrations, so 112 syringes. None of the vendors priced on this site sells syringes, alcohol pads or a sharps container. They are ordinary pharmacy items in most places and restricted in some. The count below is what the plan requires; where to obtain them is outside what this site can tell you.112 × —Not sold here
Total, compounds and water$330.61

Above this vendor's published $99 free-shipping threshold.

We earn nothing from this link. Loti Labs has no affiliate programme.

Pure Health Peptides

Prices as of 2026-08-24

$185.98

$6.64/day · $202.19/month

SemaxSemaxThis listing is sold in several vial sizes and the figure shown is the cheapest one, so the real price is higher. The listing does not publish a vial size, so the vial count is the plan's own and may not match what ships.4 × $23.00$92.00
SelankSelankThis listing is sold in several vial sizes and the figure shown is the cheapest one, so the real price is higher. The listing does not publish a vial size, so the vial count is the plan's own and may not match what ships.3 × $24.00$72.00
Bacteriostatic waterBacteriostatic Water · 10 mLThis plan uses 14.0 mL across every reconstitution. 6.0 mL is left over, because bottles do not divide.The only size this vendor sells. Stock was reported as one unit remaining when read.2 × $10.99$21.98
Syringes112 administrations, so 112 syringes. None of the vendors priced on this site sells syringes, alcohol pads or a sharps container. They are ordinary pharmacy items in most places and restricted in some. The count below is what the plan requires; where to obtain them is outside what this site can tell you.112 × —Not sold here
Total, compounds and water$185.98

$11.00 below the published $175 free-shipping threshold.

We earn nothing from this link. No affiliate programme was found for this vendor.

Peptira

Prices as of 2026-08-25

$252.65

$9.02/day · $274.67/month

SemaxSemax · 10 mg$4.90/mg listed · $5.83/mg after what expires unusedPriced at the 10 mg size rather than the 5 mg this plan assumes, because across the sizes this vendor stocks it works out cheapest for the whole course. Vial count re-simulated at that strength.2 × $49.00$98.00
SelankSelank · 10 mg$4.66/mg listed · $4.99/mg after what expires unused3 × $46.55$139.65
Bacteriostatic waterBAC Water 10ML · 10 mLThis plan uses 10.0 mL across every reconstitution.1 × $15.00$15.00
Syringes112 administrations, so 112 syringes. None of the vendors priced on this site sells syringes, alcohol pads or a sharps container. They are ordinary pharmacy items in most places and restricted in some. The count below is what the plan requires; where to obtain them is outside what this site can tell you.112 × —Not sold here
Total, compounds and water$252.65

$12.35 below the published $250 free-shipping threshold.

Peptira runs an affiliate programme. This site has not applied to it, so no commission is earned on this link today.

List price is not the price anyone pays

All three vendors run frequent site-wide promotional codes: commonly 20 to 40 percent at Loti Labs, and a permanent-looking banner advertising up to 50 percent in the cart at Peptira. Those codes are not captured here and cannot be, because they change weekly and are not published in any stable form. Treat every figure above as an upper bound on a list basis, read on the date shown, and check the vendor’s own cart before committing to anything. Ordering is by price. It is not influenced by which vendors pay us, and today none of them do.

What usually goes wrong

Ranked by how often it happens rather than by how serious it sounds.

Quoting a Russian trial as the source of a per-dose figure

This is the most common error in this category, and it is the reason both figures above carry a community badge rather than a trial badge. The trials exist. The doses are not in them.

Not knowing which concentration you bought

0.1% is 1 mg/mL. 1% is 10 mg/mL. The same number of drops delivers ten times the mass. Listings frequently omit the concentration entirely.

Running continuously because it is a nasal spray

The published Russian courses were five to ten days, sometimes repeated after a twenty-day break. Continuous multi-week use is a community convention with no counterpart in the literature.

Assuming regulatory acceptance follows from foreign approval

Selank acetate appears on the FDA's withdrawn-nomination list for 503A compounding. Registration in one jurisdiction is not a finding about safety in another.

What is worth measuring

Markers that would actually tell you something, and what each one tells you. Nothing here is a requirement, and none of it substitutes for a clinician who knows your history.

MarkerWhenWhat it tells you
A validated anxiety or mood scaleBaseline and weeklyThe endpoint the Selank trial actually measured, and the only comparable signal available.
Sleep qualityOngoingCommonly reported to change on both compounds, in both directions.
Nasal mucosaOngoingRepeated intranasal administration of any peptide solution is locally irritant in some people.

Populations this was not studied in

An absence of evidence in a group is not evidence of safety in that group. These are listed because the gap itself is the finding.

  • Anyone — no trial has tested these two together
  • Pregnancy and breastfeeding
  • Anyone taking a benzodiazepine or an SSRI, which the originating trials used as comparators rather than co-medications
  • Anyone under 18

Protocol last reviewed 2026-08-25. Every quantity on this page carries its own source. If you find one that does not, that is a bug and the build should have caught it.